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Get Complete Medical Information About Misoprostol Including Its Uses, Side Effects, Interactions, Expert Advice, Faqs Of Misoprostol On



MISOPROSTOL is an anti-ulcer agent. MISOPROSTOL is used to treat and prevent ulcers in the stomach and intestine.

Common side-effects

• Diarrhoea
• Skin rashes
• Dizziness
• Headache
• Stomach pain
• Constipation

It is not necessary for all people to experience the above side-effects.


• Take MISOPROSTOL with food to avoid stomach upset.
• Taking MISOPROSTOL in the morning will effectively reduce stomach acid production for a long duration during the day.
• Avoid spicy meals, citrus fruits, lemons and pickles to reduce acid reflux incidences.
• Usually MISOPROSTOL is not recommended for children and adolescents.
• Breast feeding women are recommended to avoid taking MISOPROSTOL as it may cause diarrhoea in infants.
• Check with your doctor before taking any medicines while using MISOPROSTOL.
• Before driving or performing any strenuous activity after taking MISOPROSTOL make sure you are alert and normal enough to take up the above activities as this medicine may induce sleepiness and dizziness.
• Inform your doctor if you have low or high blood pressure, inflammatory bowel disease or heart disease.
• Bring to your doctor’s notice if you are prone to dehydration because MISOPROSTOL may cause dehydration due to diarrhoea. So, severe dehydration can damage your kidneys.


Q. How does MISOPROSTOL work? A. Reduced prostaglandin levels lead to peptic ulcers. MISOPROSTOL works by mimicking the action of natural prostaglandins. MISOPROSTOL binds to stomach receptors and stimulate the production of protective mucus and mucus coats the damaged lining area of stomach and intestine and reduces stomach acid production.
Q. Can I take MISOPROSTOL during pregnancy? A. No, pregnant women or woman trying to conceive are recommended to avoid taking MISOPROSTOL because MISOPROSTOL may cause miscarriage, premature birth or birth defects. Pregnant women who have taken MISOPROSTOL during the first trimester has three-fold increased risk of birth defects such as limb defects, facial paralysis, cerebral and cranial abnormalities. Men and women are advised to use effective contraception while using MISOPROSTOL. 
Q. Does MISOPROSTOL cause diarrhoea? A. Yes MISOPROSTOL is known to cause diarrhoea because MISOPROSTOL contains castor oil. Ricinoleic acid (fatty acid) of castor oil binds to smoothen muscle receptors of intestinal walls and cause loosen stools and increases bowel movements which thereby leads to diarrhoea and upset stomach.
Q. Can I take MISOPROSTOL with magnesium-containing antacids (used to treat stomach acidity)? A. No, you are recommended to not to take MISOPROSTOL with magnesium-containing antacids because MISOPROSTOL with magnesium-containing antacids may increase the risk of diarrhoea and worsen existing diarrhoea, which is a one of the common side effects of MISOPROSTOL.
Q. Does MISOPROSTOL prevent peptic ulcers? A. Yes, MISOPROSTOL prevents non-steroidal anti-inflammatory drugs (NSAIDs) induced peptic ulcers. NSAIDs reduces the gut protective prostaglandins production and cause peptic ulcers. So, MISOPROSTOL helps in preventing peptic ulcers in people who are taking NSAIDs for long-term to treat conditions like arthritis.