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Get Complete Medical Information About Letrozole Including Its Uses, Side Effects, Interactions, Expert Advice, Faqs Of Letrozole On



LETROZOLE is an aromatase inhibitor used to treat breast cancer in post-menopause women. LETROZOLE helps prevent recurrence of breast cancer. Additionally, used to treat ovulatory infertility.

Common side-effects

• Hot flushes
• Headache
• Depression
• Dizziness
• Fatigue
• Increased sweating

It is not necessary for all people to experience the above side-effects.


• Take LETROZOLE irrespective of meals daily at same time for best results.
• Do not give LETROZOLE to children and adolescents.
• Please do not take more than prescribed LETROZOLE as it may cause some very serious adverse effects.
• Inform your doctor if you are taking any other medicines, because they may affect the way LETROZOLE is working and vice versa.
• Inform your doctor if you still have menstrual periods because LETROZOLE is used for women who have gone through the menopause.
• Also, inform your doctor if you have or had kidney or liver diseases.
• Bring to your doctor's knowledge if you have or had any history of osteoporosis (weak bones), because LETROZOLE cause osteoporosis.


Q. How does LETROZOLE work? A. LETROZOLE blocks aromatase enzyme (natural substance which helps producing oestrogen hormone) and reduces oestrogen hormone production. Few breast cancers grow faster by oestrogen hormone hence LETROZOLE acts on aromatase and reduces oestrogen hormone levels.
Q. How does LETROZOLE works in inducing ovulation (release of eggs from ovaries)? A. LETROZOLE lowers oestrogen levels which leads increase of few hormone levels like LH and FSH. Increased levels of LH and FSH stimulate follicles (helps in secreting hormones which influence menstrual cycle stages).
Q. Should I need to follow any special diet while taking LETROZOLE? A. There is no specific diet as LETROZOLE is not affected by food. You can take regular diet but try to avoid intake of high cholesterol food as LETROZOLE may increase the cholesterol levels in some cases.
Q. Does LETROZOLE cause joint pains? A. Yes, LETROZOLE cause joint pains. It is may be due to oestrogen level decrease. Low levels of oestrogen hormone cause cartilage (elastic tissue that covers and protects bone joints) loss.
Q. Can I take LETROZOLE with oestrogen medicines? A. No, it is not recommended to take LETROZOLE along with oestrogen medicines. Medicines with oestrogen interact LETROZOLE and might lead to decrease the efficiency of LETROZOLE. 
Q. What if I take more than prescribed dose? A. If you take more than the prescribed dose, immediately inform your family members or friends and call your doctor or go to the nearest hospital. Carry the medicine strip or bottle with you, even if it is empty. Do not panic if you experience headache, sleepiness and joint pains.
Q. Can I take LETROZOLE if I have intolerance to sugars? A. No, LETROZOLE contains lactose (milk sugar) and it may possibly cause stomach upset. Discuss with your doctor regarding sugar intolerance before taking LETROZOLE.