Ketoconazole Tablet: Uses, Dosage, Side Effects, Composition & More - Zoylo
INFORMATION ABOUT KETOCONAZOLE
KETOCONAZOLE is an antifungal agent. KETOCONAZOLE is used to treat various fungal and yeast infections in those who are intolerant to other antifungal therapies. It treats blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis infections.
• Hot flush
It is not necessary for all people to experience the above side-effects.
SPECIAL INSTRUCTIONS FOR KETOCONAZOLE
• Take KETOCONAZOLE with food daily at the same time for best results.
• While taking KETOCONAZOLE, avoid consumption of alcohol as some people may experience rashes, swelling of the ankles, flushing, headache or nausea.
• Pregnant women, women trying to conceive, and breast-feeding mothers are recommended to check with your doctor before taking KETOCONAZOLE.
• You are advised not to take indigestion remedies and KETOCONAZOLE at the same time because KETOCONAZOLE may not get absorbed properly.
• Inform your doctor if you are taking medicines from long QT syndrome because KETOCONAZOLE may worsen the condition if it interacts with the medicines used for treating QT prolongation.
• Check with your doctor before taking any medicines while taking KETOCONAZOLE because few medicines may affect the way KETOCONAZOLE works and vice versa.
FREQUENTLY ASKED QUESTIONS
Q. How does KETOCONAZOLE work? A. Cell membranes play essential role for the survival of fungi. KETOCONAZOLE works by inhibiting essential component of fungal cell membranes i.e., ergosterol and cell membrane disintegration leads to fungal death which results in clearing the infection.
Q. Does KETOCONAZOLE treat fungal nail infections? A. No, KETOCONAZOLE is not used to treat fungal nail infections due to the increased risk of serious adverse effects and drug interactions. Your doctor will diagnose and prescribe right treatment for you.
Q. Does KETOCONAZOLE make hormonal contraceptives (pill) less effective? A. Yes, KETOCONAZOLE may make hormonal contraceptives less effective. You are recommended to use other methods of contraception while using KETOCONAZOLE to prevent pregnancy.
Q. Does KETOCONAZOLE cause hepatotoxicity (Liver toxicity)? A. Yes, KETOCONAZOLE is known to cause hepatotoxicity. Liver plays a central role in transforming and clearing drugs or toxins. KETOCONAZOLE inhibits an enzyme (speed up chemical reactions in the body) i.e., CYP3A4 which is present in liver and intestine. Usually, CYP3A4 oxidizes toxins or drugs, so due its inhibition, liver does not remove the toxins from the liver which in turn leads to build up of toxins in liver causing hepatotoxicity.
Q. Can I take warfarin while taking KETOCONAZOLE? A. No, you are strongly recommended not to take warfarin along with KETOCONAZOLE. KETOCONAZOLE with warfarin might increase the risk of bleeding and increase the time for bleeding to stop. Please check with your doctor before taking any medication.